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Rabbit Anti-ANGPTL3  antibody (bs-25370R)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號 bs-25370R
英文名稱 Rabbit Anti-ANGPTL3  antibody
中文名稱 血管生成素樣蛋白3抗體
別    名 ANG 5; ANG-5; ANG5; Angiopoietin 5; Angiopoietin like 3; Angiopoietin related protein 3; Angiopoietin-5; Angiopoietin-like protein 3; Angiopoietin-related protein 3; ANGL3_HUMAN; ANGPT5; FHBL2.  
研究領(lǐng)域 腫瘤  心血管  細胞生物  免疫學  信號轉(zhuǎn)導(dǎo)  生長因子和激素  血管內(nèi)皮細胞  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Rat (predicted: Human,Mouse,Pig,Sheep,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 49kDa
細胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ANGPTL3: 1-100/460 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Angiopoietin-like protein 3 (Angptl3) functions as a potent lipoprotein lipase inhibitor and is an important component of plasma triglyceride homeostasis. Angptl3 also plays a role in adipose formation and angiogenesis through its interaction with integrin ?v)beta(3). It is secreted by the liver and is functionally defined by the C-terminal fibrinogen (FBN)-like domain and an N-terminal coiled-coil domain. Angptl3 regulates circulating triglyceride levels during different nutritional states thereby mediating the feeding/fasting cycle. A deficiency of Angptl3 results in abnormally low lipid levels, and a repression of the protein may be protective against atherosclerosis. Angptl3 may also play an important role in hyperlipidemia in diabetes.

SWISS:
Q9Y5C1

Gene ID:
27329

Database links:

Entrez Gene: 27329 Human

Entrez Gene: 30924 Mouse

Entrez Gene: 502970 Rat

Omim: 604774 Human

SwissProt: Q9Y5C1 Human

SwissProt: Q9R182 Mouse

Unigene: 209153 Human

Unigene: 28341 Mouse



產(chǎn)品圖片
Sample: Lane 1: Rat Liver tissue lysates Lane 2: Rat Testis tissue lysates Primary: Anti-ANGPTL3 (bs-25370R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 49 kDa Observed band size: 27 kDa
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