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Rabbit Anti-BTBD1  antibody (bs-9294R)
~~~促銷代碼KT202410~~~
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說明書: 50ul  100ul  200ul
50ul/1180.00元
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200ul/2800.00元
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產品編號 bs-9294R
英文名稱 Rabbit Anti-BTBD1  antibody
中文名稱 BTB/POZ結構域蛋白1抗體
別    名 BTB (POZ) domain containing 1; BTB domain containing 1; BTB/POZ domain containing protein 1; BTBD 1; BTBD1; C15orf1; HCV NS5A transactivated protein 8; Hepatitis C virus NS5A transactivated protein 8; NS5ATP8; BTBD1_HUMAN.  
研究領域 細胞生物  細胞周期蛋白  轉錄調節因子  細菌及病毒  細胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat (predicted: Human,Mouse,Pig,Sheep,Cow,Dog,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 53kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BTBD1: 101-200/482 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 BTBD1 contains a proline-rich region and a BTB/POZ domain which are typically involved in protein-protein interactions. The C-terminus of BTBD1 binds topoisomerase I and BTBD1 also interacts with TRIM5 isoform Delta. BTBD1 localizes to cytoplasmic bodies and is essential for myogenic differentiation.

Function:
Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Subunit:
Interacts with topoisomerase 1 and with TRIM5 isoform Delta. Interacts with CUL3.

Subcellular Location:
Cytoplasm, P-body. Cytoplasmic bodies.

Tissue Specificity:
Ubiquitous; higher levels in heart and skeletal muscle.

Similarity:
Contains 1 BTB (POZ) domain.

SWISS:
Q9BSF8

Gene ID:
84280

Database links:

Entrez Gene: 84280 Human

Entrez Gene: 68815 Mouse

Entrez Gene: 308890 Rat

SwissProt: Q9BSF8 Human

SwissProt: Q80X66 Mouse



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